Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound

University of Virginia

Status: Unknown

Conditions: Kidney

Treatments: Drug: perflutren lipid microspheres

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00631553

12014

Details and patient eligibility

About

The purpose of this study is to determine if contrast enhanced ultrasound (CEU) using microbubbles, is useful in assessing changes in kidney blood flow.

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults
• Males and females
• Ages 18-65 years old

Exclusion criteria

• Pregnancy or lactation
• H/o kidney disease
• H/o congestive heart failure, ischemic heart disease, severe pulmonary disease or allergy to the drug
• H/o any cardiovascular disease
• Abnormal liver function (liver function tests out of specified ranges)
• Screening urinalysis which indicates infection or inflammation
• Taking regular medications (except for over-the-counter vitamins or hormonal contraceptives.)
• Taking supplements, like protein shakes
• Unwilling or unable to eat chicken (used as protein meal)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)