Assessment of Clinically Related Outcomes and Biomarker Analysis for Translational Integration in Colorectal Cancer (ACROBATICC)

Helse Stavanger HF

Status: Enrolling

Conditions: Colorectal Cancer

Treatments: Procedure: open and laparoscopic surgery

Study type: Observational

Funder types: Other

Identifiers

NCT01762813

29034/2012

Details and patient eligibility

About

• A prospective, observational study on clinical outcomes of surgical management of primary and metastatic colorectal cancer
• Prospective collection of tissues to explore potential biomarkers in blood and/or primary or secondary cancers and/or normal colon

Full description

Prospective project in collecting and assessing clinical outcomes data related to molecular profiling of tumors based on cancer primary or metastatic tissue or tissue from peripheral blood samples. As a future part of the project will be collected patient reported outcomes (PROs) for assessing clinical outcomes in relation to clinical pathways, patient reported results, as well as tumor profiling by molecular methods.

Enrollment: 1,200 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of colorectal cancer, primary or metastatic (liver), with a treatment intention of planned curative surgery
• Informed consent to participate
• Age ≥18

Exclusion criteria

• failure to provide written informed consent

Trial design

1,200 participants in 1 patient group

open and laparoscopic surgery

Description:

Patients with primary and or metastatic colorectal cancer (CRC) eligible for curative surgery will be included. Subcohorts may be based on either colon cancer, rectal cancer, metastatic cancer, surgery (laparoscopy or open), node negative and node positive disease, and molecular profiling.

Treatment:

Procedure: open and laparoscopic surgery