Assessment of Coronary Artery Disease in Stroke Patients (ACADIS)

Seoul National University

Status: Completed

Conditions: Coronary Artery Disease

Study type: Observational

Funder types: Other

Identifiers

NCT01850693

NRF 2010-0023504

Details and patient eligibility

About

This study is to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of coronary atherosclerosis in stroke patients with coronary CT angiography.

Full description

Stroke and coronary artery disease (CAD) share common risk factors and pathological mechanisms. CAD is an important cause of death in patients with stroke.

Currently, coronary CT angiography (CCTA) is very useful non-invasive tool for detection of CAD and plaque analysis.

Therefore, the investigators aimed to evaluate the prevalence, plaque characteristics (plaque types, stenosis degree, remodeling) and predictors of CAD in stroke patients through follow-up (more than 5 years) using CCTA.

Enrollment: 1,657 patients

Sex: All

Ages: 30+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute stroke patients who diagnosed by clinical and brain MR imaging
• Who performed coronary CT angiography within 3 months after acute stroke

Exclusion criteria

• intracranial hemorrhage including intracerebral, subdural or subarachnoid hemorrhage
• brain tumor
• Previous myocardial infarction
• Previously performed percutaneous coronary intervention (PCI), coronary artery bypass graft (CABG) or other cardiac surgery
• Insufficient medical record
• Poor image quality of CCTA scan

Trial design

1,657 participants in 1 patient group

Coronary artery disease, Stroke

Description:

Coronary artery disease, stroke, coronary CT angiography