Assessment of Coronary Flow Reserve by PET-H215O and FFR. Comparison With Dynamic Acquisition Using CZT Camera (WATERDAY)

Caen University Hospital

Status

Unknown

Conditions

Coronary Artery Disease

Treatments

Other: ASSESSMENT OF CORONARY FLOW RESERVE BY PET-H215O AND FFR

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT02278497

14-006

Details and patient eligibility

About

The study will assess coronary flow reserve by PET-H215O and FFR in patients suspected of coroanry artery disease. This a comparative study with dynamic acquisition using CZT camera and 99mcTc-mibi. 20 patients will have those measurements.

Enrollment

20 estimated patients

Sex

All

Ages

18 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patient between 18 and 80 years
Suspected coronary disease and / or coronary syndrome patient ST-
Patient who has been informed of the study and has given his informed consent
Patient affiliated to a social security system.

Exclusion criteria

Patient having no coronary disease at coronary angiography with FFR on the 3 main epicardial arteries (absence of ≥ 50% stenosis of at least one artery)
Delay of Care grater than 30 days between the PET and SPECT imaging and the diagnostic coronary angiography
Patient with a recent history of myocardial infarction and STEMI, unstable angina
Patient with extra-cardiac disease whose prognosis can interfere with the treatment decision
Pregnant or lactating women
Patient allergic to contrast products during coronary angiography
Patient with MDRD clearance les than 60 ml / min
Patient Under guardianship, or unable to understand the purpose of the study