Assessment of Endocan Serum Levels in Patients With Behcet Disease

Benha University

Status: Completed

Conditions: Behçet

Treatments: Diagnostic Test: measurement of serum endocan

Study type: Observational

Funder types: Other

Identifiers

NCT03853135

BenhaU22019

Details and patient eligibility

About

The aim of our study was to assess serum endocan levels in patients with Behcet disease and to correlate it with various disease clinical and laboratory parameters of disease activity as well as carotid intima media thickness.

Full description

This study will be carried out on two groups:

• Group (I): Forty two patients diagnosed to have Behcets disease fulfilling the International Criteria for BD .

Group (II): including 42 age and sex matching healthy volunteers as control group.

(A) Clinical evaluation

1. Complete history taking.
2. Thorough clinical examination including opthalmologic evaluation .
3. Disease activity using The Behcet's disease current activity form (BD-DAF) . (B) Laboratory assessment:

All patients will be subjected to the following measurements:

1. ESR
2. CRP
3. CBC
4. liver and kidney function tests

d) Serum Endocan level e)triglycrides f) cholestrol C) carotid intima media thickness

Enrollment: 84 patients

Sex: All

Ages: 16+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• patients with Behcets disease fulfilling the International Criteria for BD .

Exclusion criteria

• infection
• malignancy
• other connective tissue disease
• chronic liver disease
• chronic kidney disease
• Diabetes mellitus
• hypertension
• hyperlipidemia

Trial design

84 participants in 2 patient groups

Behçet group

Description:

Forty two patients diagnosed to have Behçet disease fulfilling the International Study Group Criteria for Behçet disease in whom measurement of serum endocan levels will be performed.

Treatment:

Diagnostic Test: measurement of serum endocan

control group

Description:

including 42 age and sex matching healthy volunteers as control group in whom measurement of serum endocan levels will be performed.

Treatment:

Diagnostic Test: measurement of serum endocan