Assessment of Esophageal Motility With Transnasal Endoscopy

The Catholic University of Korea

Status: Unknown

Conditions: Esophageal Motility Disorder

Study type: Observational

Funder types: Other

Identifiers

NCT01658865

NE-EM-001

Details and patient eligibility

About

The purpose of this study is to assese esophageal motor function by simplified transnasal endoscopy compared with esophageal manometry.

Full description

Esophageal manometry is a gold standard for diagnosis of esophageal motility disorder. However, esophageal manometry can not detect non-occulsive contraction. Endoscopic evaulation of esophageal motility is difficult becausea swallowing is nearly impossible during endoscopy. Simplified trans nasal endoscopy (E.G. ScanTM, IntroMedic Co.,Ltd.)composed with dysplay system,controller,and disposable probe with compact size.

The esophageal motor function will be assessed with both esophageal manometry and simplifed trnasnasal endoscopy in patients with esophageal motility disorder (such as achalasia) and healthy volunteer. The results of simplifed trnasnasal endoscopy is compared with the results of esophageal manometry.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 1. Healthy volunteer without organic esophageal or gastric disorder 2) Patients knwon esophageal motility disorder (such as achalasia)

Exclusion criteria

• severe organic esophageal disorder including severe reflux esophagitis, stricture, and bleeding.
• previous opertion of esophagus or stomach
• GI bleeding, mechanical obstruction
• medication which can infulence GI motility

Trial design

40 participants in 1 patient group

Transnasal endoscopy

Description:

Healthy volunteers and patients with esophageal motor symptom will be enrolled and esophageal motility assessed by transnasal endoscopy according to clinical and manometric diagnosis