Assessment of Geriatric Evaluations Impact on New AML Guidance (AGE-ING)

Abramson Cancer Center at Penn Medicine

Status: Enrolling

Conditions: AML, Adult

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT05909501

UPCC 11423

Details and patient eligibility

About

The goal of the study is to measure physiologic age (there is no current formal definition but is meant to imply that patients should be evaluated holistically rather than on age alone) at baseline in newly diagnosed AML patients over 50 years receiving either intensive or non-intensive treatment. This information will be used to evaluate toxicity, early mortality, remission rates and long term survival.

Enrollment: 100 estimated patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• AML diagnosis by peripheral flow cytometry and/or bone marrow aspirate and biopsy
• New diagnosis being considered for new line of treatment
• Age ≥ 50 years.
• Performance status 0,1, and 2

Exclusion criteria

• Inability to understand or unable to sign a written informed consent
• Unable to fill out questionnaires on their own and/or do not have someone to help complete them