Assessment of Hematopoietic Recovery Following Chemotherapy for Non-Hodgkin's Lymphoma

University of Oklahoma (OU)

Status: Terminated

Conditions: Non-Hodgkin's Lymphoma

Treatments: Procedure: FDG-PET scan; Procedure: FLT-PET scan

Study type: Observational

Funder types: Other

Identifiers

NCT00775957

FLT-NHL

Details and patient eligibility

About

A study to determine the accuracy of FLT-PET in quantifying tumor cell proliferation at the initial staging of patients with Non-Hodgkin's Lymphoma in comparison wit the "gold standard" FDG-PET.

Full description

The first primary objective reflects a necessary and preliminary requirement: to reproduce published results and validate the use of FLT-PET. In this study, 35 patients will be selected to undergoing imaging with both FLT and FDG PET.

Enrollment: 35 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years or older
• Women must not be pregnant or breast feeding
• Histologic diagnosis of non-Hodgkin's lymphoma (any stage)
• Must undergo treatment with chemotherapy and/or radiotherapy

Exclusion criteria

• May not have received previous therapy with radiopharmaceuticals
• May not have received prior therapy with cytotoxic chemotherapy and/or monoclonal antibodies

Trial design

35 participants in 2 patient groups

1

Description:

FLT-PET Scan

Treatment:

Procedure: FLT-PET scan

2

Description:

FDG-PET Scan

Treatment:

Procedure: FDG-PET scan