Assessment of Human Exposure to Chemical Hazards

National University of Singapore

Status

Enrolling

Conditions

Dietary Exposure

Treatments

Other: Food Frequency, Social, Lifestyle, Demographic Questionnaires and Blood Collection

Study type

Observational

Funder types

Other

Identifiers

NCT06526169

NUS-IRB-2024-128

Details and patient eligibility

About

The aim of this study is to evaluate the occurrence of chemical hazards exposure in the Singapore population and assess their association with food consumption.

Full description

Human biomonitoring is an exposure assessment approach with the potential value-add supplementation to existing sources of information for regulatory risk assessments and for supporting food safety policies. The collaboration involving academic partners from the sciences and public health disciplines to quantify the in vivo chemical exposure of chemicals will take reference from the findings in the Singapore's total diet study on the prioritised chemical hazards of interest for a more precise assessment of the distribution of risk in the population. Direct measurement of chemicals and/or metabolites in biological specimens obtained from study subjects will be conducted to provide a more comprehensive understanding on the baseline dietary chemical exposure in the local population. Dietary assessment using food frequency questionnaire will be administered to the same group of study subjects to associate human exposure to chemical hazards with food consumption across the different population groups in Singapore.

Enrollment

300 estimated patients

Sex

All

Ages

21 to 60 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Must be English-literate and able to give informed consent in English
21 to 60 years of age (inclusive) at screening
Healthy adults
Race must be Chinese or Indian or Malay
Reliable and willing to make themselves available for the duration of the study and are willing to follow study procedures

Exclusion criteria

Known or ongoing psychiatric disorders within 3 years
Being diagnosed with cancer, heart disease, stroke, renal failure, serious mental or physical illnesses at the time of recruitment
Have donated blood of more than 500 mL within 4 weeks of study enrolment