Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars

Future University in Egypt

Status: Enrolling

Conditions: Pulpotomy

Treatments: Procedure: pulpotomy

Study type: Interventional

Funder types: Other

Identifiers

NCT06640205

(32)/8-2023

Details and patient eligibility

About

Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars

Full description

Clinical and Radiographic Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF Scaffold in Vital Pulp Therapy in Mandibular First Molars with Closed Apices: "Randomized Controlled Trial"

Enrollment: 51 estimated patients

Sex: All

Ages: 15 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients suffering from Symptomatic irreversible pulpitis in mature mandibular molars only will be involved.

  • Patients of either gender aged from 15-30.
  • Tooth should give positive response to cold test.
  • The tooth is restorable
  • Patients should be free from any systemic disease that may affect normal healing and predictable outcome.
  • Patients who will agree to the consent and will commit to follow-up period.
  • Patients with mature root.
  • Patients with no internal or external resorption and no periapical lesions.
  • Soft tissues around the tooth are normal with no swelling or sinus tract.

Exclusion criteria

• Patients with immature roots.

  • Haemostasias after 10 minutes can not be controlled after total pulpotomy
  • Patients with periapical lesions or infections.
  • Pregnant females.
  • Patients with fistula or swelling
  • Patients with necrotic pulp.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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51 participants in 3 patient groups

MTA Pulpotomy

Active Comparator group

Description:

using MTA as pulpotomy capping agent in mature permanent teeth

Treatment:

Procedure: pulpotomy

I-PRF pulpotomy

Experimental group

Description:

using I-PRF as pulpotomy capping agent in mature permanent teeth

Treatment:

Procedure: pulpotomy

I-PRF combined with Nano MTA pulpotomy

Experimental group

Description:

using nano MTA mixed with I-prf as pulpotomy capping agent in mature permanent teeth

Treatment:

Procedure: pulpotomy