Assessment of Interactions Between Intravenous Methamphetamine and Modafinil - 1

National Institutes of Health (NIH)

Status and phase: Unknown; Phase 1

Conditions: Amphetamine-Related Disorders

Treatments: Drug: Modafinil

Study type: Interventional

Funder types: NIH

Identifiers

NCT00265278

NIDA-CPU-0008-1

Details and patient eligibility

About

The purpose of this study is to assess the potential interactions between intravenous methamphetamine and oral Modafinil.

Full description

The primary aims of this experiment are to determine if there are significant safety interactions between oral modafinil and intravenous methamphetamine. Safety will be assessed by measuring adverse events and cardiovascular responses of heart rate (HR), blood pressure (BP), and electrocardiogram (ECG) and stroke distance (ICG).

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• normotensive
• good physical and mental health
• body mass index between 18 and 30
• if female, using an acceptable method of contraception and are not pregnant
• able to give voluntary informed consent

Exclusion criteria

• Please contact site for further details

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind