Assessment of L-PRF, Nanohydroxyapatite Combined With L-PRF Using Pulpotomy in Mature Mandibular First Molars

Future University in Egypt

Status: Enrolling

Conditions: Irreversible Pulpitis

Treatments: Procedure: pulpotomy

Study type: Interventional

Funder types: Other

Identifiers

NCT06613932

(37)11-2023

Details and patient eligibility

About

Clinical and Radiographic Assessment of L-PRF, Nanohydroxyapatite material combined with L-PRF scaffold in Vital pulp Therapy. Treatments in Mandibular First Molars with Closed Apices, Randomized Controlled Trial.

Full description

pulpotomy by using 3 materials. The first group(control group ) uses hydroxyapatite material as a pulpotomy agent, and the second group uses L-PRF as a pulpotomy agent. the third group uses combined material (L-PRF = Nano hydroxyapatite )as a pulpotomy agent .. then assesses the clinical and radiographic result of the 2 interventions group with control group

Enrollment: 45 estimated patients

Sex: All

Ages: 15 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Patients should be free from any systemic disease. Patients of either gender aged from 15-30. Patients will agree to the consent and will commit to a follow-up period. Soft tissues around the tooth are normal with no swelling or sinus tract. The tooth is restorable tooth has signs and symptoms of irreversible pulpitis of the mature root The tooth doesn't contain any internal or external resorption or periapical lesions.

The tooth should give a positive response to the cold test.

Exclusion criteria

Pregnant and lactating females. Patients with Mental disturbance. Patients who could/would not participate in a 6-month follow-up. A tooth with immature roots. Patients with necrotic pulp.• tooth with periapical lesions or infections. Soft tissue having fistula or swelling Homoeostasis after 10 minutes can not be controlled after total pulpotomy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 3 patient groups

hydroxyapatite

Experimental group

Description:

using hydroxyapatite as a pulpotomy agent and reviewing its clinical and radiographic performance compared to the other groups

Treatment:

Procedure: pulpotomy

L-PRF

Experimental group

Description:

using L-PRF as a pulpotomy agent and assessing the clinical and radiographic result compared to other groups

Treatment:

Procedure: pulpotomy

L-PRF combined with Nano-hydroxyapatite

Experimental group

Description:

using the combined material (nanohydroxyapatite mixed to L-PRF ) and assessing the clinical and radiographic result compared to other groups

Treatment:

Procedure: pulpotomy