Assessment of Left Ventricular Diastolic Function in Patients With Atrial Fibrillation (DIAAF)

Yonsei University

Status: Unknown

Conditions: Atrial Fibrillation

Study type: Observational

Funder types: Other

Identifiers

NCT04654806

4-2020-1105

Details and patient eligibility

About

This study is a single-center, prospective cohort study to investigate non-invasive method to assess left ventricular diastolic function using echocardiography. Patients with AF who are referred radiofrequency catheter ablation (RFA) will be included prospectively. Transthoracic echocardiography will be performed during, immediately before RFA and with no cardiovascular medication taken between the exams so that the loading conditions during catheterization and echocardiography are as similar as possible. We will validate previously proposed echocardiographic parameters and creat an algorithm to identify the relationship between echocardiographic parameters of diastolic function and invasively measured LA pressure in patients with atrial fibrillation.

Enrollment: 200 estimated patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult ≥ 19 year-old
• Patients who scheduled to perform radiofrequency catheter ablation for atrial fibrillation
• Patients who had paroxysmal, persistent, or chronic AF
• Patients provided with the written, informed consent to participate in this study

Exclusion criteria

• Patients with prosthetic valve
• Life expectancy < 12 months
• Subject who the investigator deems inappropriate to participate in this study