Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease

The Ohio State University

Status: Completed

Conditions: Allogeneic Stem Cell Transplant; Acute Graft-versus-Host Disease

Treatments: Procedure: Blood samples

Study type: Observational

Funder types: Other

Identifiers

NCT01521039

OSU-11002

Details and patient eligibility

About

Assessment of MicroRNA Expression in Acute Graft-versus-Host Disease (GVHD).

Full description

The purpose of this study is to examine whether the expression levels of a novel class of molecules, called microRNAs, are associated with acute graft-versus-host disease frequency and severity. Acute graft-versus-host disease is a Acute GVHD is a medical condition that can become very serious. It happens when the donor cells attack and damage your tissues after transplant.

Enrollment: 259 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• Patients who are receiving allogeneic stem cell transplantation at the Ohio State University Blood and Marrow Transplantation program are eligible and will be consented for the study.

Trial design

259 participants in 1 patient group

Allogeneic SCT recipients

Description:

Patients who are receiving allogeneic stem cell transplantation at the Ohio State University are eligible and will be consented for the study.

Treatment:

Procedure: Blood samples