Assessment of Niacinamide Cosmetic Product Efficacy in Model of Irritant Contact Dermatitis

University of Split

Status: Enrolling

Conditions: Contact Dermatitis

Treatments: Other: niacinamide cosmetic product; Other: placebo

Study type: Interventional

Funder types: Other

Identifiers

NCT06331390

2181-198-03-04-24-0008

Details and patient eligibility

About

Testing the effectiveness and safety of cosmetics with niacinamide in irritant contact dermatitis: A Randomised, Controlled Trial will be conducted at USSM. Healthy volunteers will be included (at least 25) and test sites are forearms. Sodium lauryl sulphate will be used to induce contact dermatitis and participants will be measured for 7 days

Full description

The efficacy of niacinamide cosmetic product on contact dermatitis will be evaluated using Courage Khazaka device and probes for hydration, redness and transepidermal water loss

Enrollment: 25 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• young, healthy volunteers who gave written informed consent

Exclusion criteria

• skin disease, skin damage on measurement sites, use of corticosteroids and immunomodulators a month prior to the inclusion and during the trial, non-adherence to the trial protocol, exposure to artificial UV radiation, pregnancy and lactation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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25 participants in 2 patient groups, including a placebo group

intervenition

Experimental group

Description:

immortela cosmetic product

Treatment:

Other: niacinamide cosmetic product

placebo

Placebo Comparator group

Description:

nothing

Treatment:

Other: placebo