Assessment of Normal Values of Esophagogastric Junction (EGJ) Distensibility in Healthy Volunteers

Maastricht University Medical Centre (MUMC)

Status: Unknown

Study type: Observational

Funder types: Other

Identifiers

NCT01956877

NL45176.068.13

Details and patient eligibility

About

To assess normal values of EGJ distensibility in healthy volunteers.

Enrollment: 15 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. No history of gastrointestinal disease, especially gastro-esophageal reflux disease
2. BMI = 18-30 kg/m²
3. Caucasian race
4. Subject signed the informed consent form and is able to adhere to study protocol

Exclusion criteria

1. Age < 18 years
2. Previous esophageal or gastric surgery
3. Co-morbidities (including cardiopulmonary disease, collagen diseases, obesity, coagulation disorders and co-morbidity hindering upper gastrointestinal endoscopy)
4. Patients using anticoagulants
5. Patients unable to give informed consent
6. Smoking
7. History of alcohol abuse or current excessive alcohol consumption (> 2 alcoholic beverages per day or > 14 alcoholic beverages per week)

Trial design

15 participants in 1 patient group

Healthy volunteers