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Assessment of Peripheral Veins Doppler Ultrasound for Diagnosis of Acute Right Heart Failure in Suspicion or Follow-up of Pulmonary Hypertension (CODOVEIN)

P

Poitiers University Hospital

Status

Completed

Conditions

Acute Right Heart Failure
Peripheral Veins Doppler Ultrasound
Pulmonary Hypertension

Treatments

Diagnostic Test: Peripheral veins Doppler ultrasound

Study type

Interventional

Funder types

Other

Identifiers

NCT04792879
2021-A00100-41

Details and patient eligibility

About

Occurrence of acute right heart failure (ARHF) remains common during pulmonary hypertension (PH). Right atrial pressure (RAP) invasive measurement is the gold standard to diagnose ARHF in order to improve diuretic treatment management. Existence of indirect signs of ARHF on venous Doppler ultrasound waveform has long been described, but correlation with RAP has not been properly established yet. It is the aim of our study in order to obtain an additional tool to manage ARHF.

Enrollment

103 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult patient (age ≥ 18 years old)
  • Patient referred to the cardiology department for a right heart catheterization with measurement of RAP, regardless of the indication.
  • Free subject, without guardianship or curatorship or subordination
  • People affiliated to or beneficiary of a social security schemes
  • Informed consent signed by the patient after clear and fair information about the study.

Exclusion criteria

  • Minor patient (age < 18 years)
  • Refusal to participate in the study
  • Patient with hemodynamic instability, unable to tolerate a delay in treatment caused by the ultrasound examination.
  • Patient requiring diuretic treatment within the next 4 hours
  • Patient with a life expectancy of less than 24 hours.
  • History of proximal deep venous thrombosis involving the inferior vena cava and/or common iliac veins and/or femoral veins.
  • History of extrinsic venous compression on the inferior vena cava and/or common iliac veins and/or femoral veins.
  • Persons who do not benefit from a Social Security scheme or who do not benefit from it through a third party.
  • Persons benefiting from reinforced protection, namely minors, pregnant and nursing women, persons deprived of liberty by a judicial or administrative decision, persons staying in health or social institutions, adults under legal protection and finally patients in emergency situations.

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

103 participants in 1 patient group

Peripheral veins Doppler ultrasound
Experimental group
Treatment:
Diagnostic Test: Peripheral veins Doppler ultrasound

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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