Assessment of Post-traumatic Stress Disorder (PTSD) in Patients Monitored for Cytomegalovirus (CMV) Seroconversion During Pregnancy, (PTSD CMV)

Civil Hospices of Lyon

Status: Completed

Conditions: Pregnancy Related; Cytomegalovirus Infections; Mothers

Treatments: Other: Assessment of post-traumatic stress disorder using the Perinatal Post-traumatic Stress Disorder)

Study type: Observational

Funder types: Other

Identifiers

NCT04658810

69HCL20_1014

Details and patient eligibility

About

Reports of maternal seroconversion to CMV during pregnancy can be extremely stressful. This virus is little known to the general public and searching for information on the Internet quickly leads to a consultation of a site mentioning the risk of severe psychomotor retardation in the event of prenatal cytomegalovirus infection.

The psychological repercussions in the event of prenatal CMV infection with criteria of severity, leading or not to a request for IMG, is undeniable, but no study has investigated the consequences of seroconversion to CMV without transmission of the virus to the patient fetus, or in the case of transmission without criteria of seriousness, on the patient's experience during and after her pregnancy. Such a study would, if necessary, improve the care and support of these future mothers

Enrollment: 87 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults
• Referred to the 3 DAN centers with maternal seroconversion to CMV during their pregnancy, confirmed, with or without confirmed prenatal transmission.
• Presence of ultrasound signs without criteria of seriousness if the materno-fetal infection is proven.
• Support between January 1, 2008 and December 31, 2020.
• No opposition from patient

Exclusion criteria

• Reversed or anteconceptional CMV seroconversion
• Concomitant infection with another infectious agent and suspected cross-reaction
• Multiple pregnancy
• Ultrasound and / or MRI severity criteria
• Medical termination of pregnancy
• Fetal death in utero
• Birth <32 weeks and / or birth weight <1500 grams (birth criteria in maternity level IIA)
• Intercurrent event that may be the cause of an abnormality in psychomotor development
• Patients protected by justice