Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1

National Institutes of Health (NIH)

Status and phase: Completed; Phase 1

Conditions: Cocaine-Related Disorders

Treatments: Drug: Atomoxetine

Study type: Interventional

Funder types: NIH

Identifiers

NCT00265265

NIDA-CPU-0010-1

Details and patient eligibility

About

The purpose of this study is to assess potential interactions between intravenous (i.v.) cocaine and atomoxetine (Strattera) administered orally in four escalating doses.

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18-45 years of age who are not seeking treatment at the time of the study
• Must be able to provide written informed consent
• Must be within 20 percent of ideal body weight and weigh at least 45 kg
• Must meet DSM0IV diagnostic criteria for cocaine abuse or dependence
• Must currently be using cocaine as confirmed by a positive BE
• If female and of child bearing potential, must agree to the use of birth control

Exclusion criteria

• please contact the site directly for more information

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Double Blind