Assessment of Pouch Emptying With MRI After Roux-en-Y Gastric Bypass (MRI pouch)

Rijnstate Hospital

Status

Completed

Conditions

Gastric Bypass

Bariatric Surgery Candidate

Pouch Emptying

Obesity, Morbid

Treatments

Other: 2 years after RYGB, no intervention. MRI measurement. Observational.

Study type

Observational

Funder types

Other

Identifiers

NCT06298162

2018-1279

Details and patient eligibility

About

A cross-sectional observational study in which pouch emptying rate is measured with MRI in good (TWL>35%) and bad responders (TWL<25%) two years after Laparoscopic Roux-en-Y Gastric Bypass (LRYGB).

Enrollment

10 patients

Sex

Female

Ages

20 to 55 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Women aged between 20 and 55 years
Patients must be able to adhere to the study visit schedule and protocol requirements
Patients must be able to give informed consent (IC) prior to any study procedures
Patients who had a follow-up period up until two years after LRYGB and have successful or unsuccessful weight loss.
Willing to be informed about incidental findings of pathology and approving of reporting this to their general physician

Exclusion criteria

Diabetes Mellitus
Menopausal
Gastrointestinal problems, gastric or intestinal diseases
Drug or alcohol addiction
Inability to stop smoking during the overnight fasting period
Pregnant or lactating
Having an intolerance or allergy for one of the components of the test product
Inability to stop medications that affect gastrointestinal emptying like antisecretory drugs, narcotics and prokinetic agents
Inability to stop medication that affects the motility of the upper gastrointestinal tract (anti-cholinergic drugs, prokinetics, theophylline, calcium blocking agents, opioids)
Having a contra-indication to MRI scanning (including, but not limited to):
- Pacemakers and defibrillators
- Intraorbital or intraocular metallic fragments
- Ferromagnetic implants