Assessment of Preload Dependency Via Measurement of Peripheral Venous Pressure During an Alveolar Recruitment Manoeuvre (PVP-StepPEP)

GCS Ramsay Santé pour l'Enseignement et la Recherche

Status: Terminated

Conditions: Intensive Care Patients

Treatments: Procedure: alveolar recruitment manoeuvre by pressure step

Study type: Interventional

Funder types: Other

Identifiers

NCT05026255

2020-A02683-36

Details and patient eligibility

About

Assessment of preload dependency via measurement of peripheral venous pressure during an alveolar recruitment manoeuvre.

Prospective multicentre open-label study of mechanically ventilated intensive care patients.

Enrollment: 21 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18 years or older, for whom the trusted person designated by the patient or, failing that, a relative has read and signed the consent form for participation in the study
• Patient hospitalised in intensive care, under sedation and controlled mechanical ventilation
• Equipped with a central venous line in the superior vena cava territory and an arterial catheter.
• Whose state of health justifies vascular filling

Exclusion criteria

• Patient under legal protection, guardianship or curatorship
• Pregnant or breastfeeding woman
• Patient not affiliated to the French social security system
• Contraindication to the realization of an alveolar recruitment maneuver

Trial design

Primary purpose: Prevention

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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21 participants in 1 patient group

mechanically ventilated intensive care patients.

Experimental group

Description:

Observational data collected for patients in intensive care under mechanical ventilation.

Treatment:

Procedure: alveolar recruitment manoeuvre by pressure step