Assessment of Primary Oxygenation and Airflow Measurement for Endoscopic Laryngeal Surgery

Johns Hopkins University

Status: Completed

Conditions: Laryngotracheal Stenosis

Treatments: Diagnostic Test: Measure Airway Resistance Across Stenosis

Study type: Observational

Funder types: Other

Identifiers

NCT03222869

IRB00096150

Details and patient eligibility

About

This research is being done to determine the resistance across stenosis in the airway.

Full description

There is significant utility in objectively measuring airflow as subjects, undergoing endoscopic laryngeal surgery, commonly have difficulties with airflow secondary to their stenosis. Easier and quicker quantification will tailor diagnosis and treatment. In order to obtain an objective measure of airflow in these participants, we will place a 20-gauge angiocatheter needle into the airway. The catheter will be in situ for a short duration during several spontaneous and non-spontaneous breaths. This will be achieved via the existing tracheostomy stoma or percutaneously via the cricothyroid membrane. This technique is commonly used to access the muscles of the larynx, however, the primary purpose will be to measure airflow in this setting.

Enrollment: 3 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients 18 years or older that require outpatient endoscopic laryngeal airway surgery, in the operating room, at a tertiary academic center.

Exclusion criteria

• Pregnancy (status will be determined by a urine test as part of standard clinical care in the preoperative setting)
• Patients that are not cleared for surgery by the preoperative evaluation
• Patients with severe laryngotracheal stenosis
• Patients who are morbidly obese (BMI > 40)
• Patients with lung disease (asthma, COPD)

Trial design

3 participants in 1 patient group

Laryngotracheal Stenosis

Description:

Patients with laryngotracheal stenosis will have pressure sensors placed proximal and distal to the stenosis. Pressure and air flow will be measured

Treatment:

Diagnostic Test: Measure Airway Resistance Across Stenosis