Assessment of Pulmonary Function in Relation to the Anesthetic Used in Patients Undergoing Bariatric Surgery

Medical University of Gdansk

Status: Enrolling

Conditions: Obesity and Obesity-related Medical Conditions

Treatments: Drug: Different drug type for conduction of general anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT06759623

KO_bariatria

Details and patient eligibility

About

It is known that more or less pronounced impairment of pulmonary function occurs after anesthesia. It has been demonstrated in the postoperative period in both patients undergoing general and regional anesthesia, in patients after intra-abdominal and superficial procedures, in overweight and normal-weight patients. It has also been shown that when general anesthesia is performed with the inhalation anesthetic sevoflurane, there is a slightly smaller reduction in lung function parameters than when only intravenous anesthetics are used.

The purpose of this study is to evaluate lung function before induction and after awakening from general anesthesia depending on the inhalational anesthetic used in obese patients undergoing bariatric surgery

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Obese patients qualified for bariatric surgery.

Exclusion criteria

• Patients who have absolute contraindications to spirometry testing, i.e:

  • with aneurysms of the aorta or cerebral arteries threatening to rupture, after recent vascular surgery
  • with increased intracranial pressure, after recent intracranial bleeding or head surgery within the cranial cavity
  • after acute conditions within 6 months prior to surgery such as stroke, myocardial infarction, unstable angina, pneumothorax
  • with uncontrolled hypertension
  • after recent eye surgery or a history of retinal detachment
  • with hemoptysis of unknown etiology. And patients unable to perform spirometry testing

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

100 participants in 2 patient groups

General anesthesia with desflurane

Experimental group

Description:

Patients undergoing anesthesia for bariatric surgery with desflurane as a volatile agent.

Treatment:

Drug: Different drug type for conduction of general anesthesia

General anesthesia with sevoflurane

Experimental group

Description:

Patients undergoing anesthesia for bariatric surgery with sevoflurane as a volatile agent.

Treatment:

Drug: Different drug type for conduction of general anesthesia