Assessment of Quality of Life in Hemophiliac Patients

Assiut University

Status

Unknown

Conditions

Improvement of Quality of Life of Hemophiliac Patients

Study type

Observational

Funder types

Other

Identifiers

NCT03159663

Assiut1987

Details and patient eligibility

About

Hemophilia is an X-linked congenital bleeding disorder caused by deficiency of coagulation factor VIII (in hemophilia A) or factor IX (in hemophilia B).

The deficiency is the result of mutations of the respective clotting factor genes.

Full description

Hemophilia is rare, with only about 1 instance in every 10,000 births (or 1 in 5,000 male births) for hemophilia A and 1 in 50,000 births for hemophilia B.

According to the World Federation of Hemophilia, 400 000 people worldwide & 5,307 people in Egypt are suffering from hemophilia.

Hemophilia A is more common than hemophilia B, representing 80-85 % of the total hemophilia population.

Signs and symptoms of hemophilia vary according to the level of clotting factors, mild, moderate and sever.

Unexplained excessive bleeding from cuts or injuries
Epistaxis without a known cause
Many large or deep bruises
Hamoarthritis
Hematuria and Melena.
Intracranial hemorrhage and death
In infants, unexplained irritability

it is subjective representation of health, including not only physical,mental and social, but also emotional and everyday life dimensions in terms of well-being. Several definitions of QoL have been provided, the definition of the WHO viewing QoL as 'individuals perceptions of their position in life in the context of culture and value systems in which they live and in relation to their goals, expectation standards and concerns'

Enrollment

100 patients

Sex

Male

Ages

10 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria