Assessment of Relationship Between Preoperative Nutritional Status and Perioperative/Postoperative Conditions in Patients With Lung Cancer Scheduled for Lobectomy

Turkish Society of Anesthesiology and Reanimation

Status: Enrolling

Conditions: Malnutrition; Lung Cancer; Nutritional Deficiency

Treatments: Diagnostic Test: Anthropometric measurements; Diagnostic Test: Nutritional Risk Screening-2002; Diagnostic Test: Nutritional Risk Index; Diagnostic Test: Prognostic Nutritional Index; Device: Handgrip strength test; Diagnostic Test: Glasgow Prognostic Score; Diagnostic Test: Mini Nutritional Assessment

Study type: Observational

Funder types: Other

Identifiers

NCT05417672

LungCancerMalnutrition

Details and patient eligibility

About

Malnutrition is common in patients with lung cancer. In patients with malnutrition risk, the risk of complications is high both in the perioperative, early and late postoperative periods. Malnutrition is an independent risk factor for length of hospital stay and cost in these patients. Patients with lung cancer may have many morbidities in postoperative period, especially problems with wound healing. Therefore, assessment of the nutritional status of patients with lung cancer should begin at the diagnosis stage.

Full description

In patients with lung cancer scheduled for lobectomy, anthropometric measurements will be measured and the results of laboratory tests(albumin, prealbumin, creatinine, total lymphocyte count, C reactive protein), Nutritional Risk Screening-2002, Nutritional Risk Index, Mini Nutritional Assessment, Glasgow Prognostic Score, Prognostic Nutritional Index and neoadjuvant chemotherapy or not will be recorded in 72 hours before surgery. In addition, demographic information of the patients (name, surname, identification number, age, comorbidity, American Society of Anesthesiologists score) will be recorded. After the information is given to the patients, their written and verbal consent will be obtained.

In the operating room, routine monitoring (electrocardiography, invasive blood pressure measurement, arterial blood gas monitoring, peripheral oxygen saturation, end-tidal carbon dioxide measurement by capnography) will be applied to the patients in accordance with the standard protocol for elective lobectomy surgery.

Hemodynamic changes (eg. dysrhythmia, hypotension, hypertension, hemorrhage), metabolic status (pH, bicarbonate, base excess), lactate, glucose level in blood gas evaluation and intraoperative complications will be recorded during the intraoperative period.

In the postoperative period, length of stay in the intensive care unit, length of hospital stay, early complications (eg. dysrhythmia, acute coronary syndrome, sepsis, mediastinitis, pneumonia, surgical site infection, prolonged air leak), time to start oral intake and transition to adequate oral intake will be recorded in the one-month postoperative period.

Enrollment: 63 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having a diagnosis of lung cancer
• Lung lobectomy operation will be performed
• 18 years and older patients
• Having an American Society of Anesthesiologists score of 1, 2, 3
• Having approved and signed the informed consent form

Exclusion criteria

• Patients who underwent lobectomy with a diagnosis other than lung cancer
• Patients younger than 18 years
• Patients with an American Society of Anesthesiologists score of 4 and above
• Patients who did not accept informed consent
• Patients who refused to participate in the study

Trial design

63 participants in 1 patient group

Lung cancer scheduled lobectomy

Treatment:

Device: Handgrip strength test

Diagnostic Test: Glasgow Prognostic Score

Diagnostic Test: Mini Nutritional Assessment

Diagnostic Test: Anthropometric measurements

Diagnostic Test: Nutritional Risk Screening-2002

Diagnostic Test: Nutritional Risk Index

Diagnostic Test: Prognostic Nutritional Index