Assessment of Response to the Conventional Periodontal Treatment Based on the Blood Group Phenotypes.

Damascus University

Status: Completed

Conditions: Chronic Periodontitis

Treatments: Procedure: nonsurgical periodontal treatment

Study type: Observational

Funder types: Other

Identifiers

NCT03644901

UDDS-Perio-03-2018

Details and patient eligibility

About

The aim of this study is to find out if one blood group phenotype is more responsive than the others to the nonsurgical periodontal treatment.

Full description

To the best of our knowledge, this is the first (research) randomized clinical trial that assesses how patient respond to the nonsurgical periodontal treatment based on their blood group phenotype.

Enrollment: 60 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• systematically healthy.
• have at least 20 teeth excluding the third molars.
• had not received any periodontal treatment or antibiotic therapy for dental or medical reason 6 month prior to the study.
• diagnosed with generalized chronic periodontitis (>30% of the sites have probing depth ≥4), and a minimum of six teeth with probing depth of 5-6 mm.

Exclusion criteria

• smokers and alcoholics.
• pregnancy.
• history of a systematic disease such as diabetes, leukemia, epilepsy.
• participants who are unable to perform routine oral hygiene.
• use of orthodontic appliances.
• participants who are unable to perform routine oral hygiene.

Trial design

60 participants in 4 patient groups

Patients whose blood type is A

Description:

Applying nonsurgical periodontal treatment (scaling and root planning).

Treatment:

Procedure: nonsurgical periodontal treatment

Patients whose blood type is B

Description:

Applying nonsurgical periodontal treatment (scaling and root planning).

Treatment:

Procedure: nonsurgical periodontal treatment

Patients whose blood type is AB

Description:

Applying nonsurgical periodontal treatment (scaling and root planning).

Treatment:

Procedure: nonsurgical periodontal treatment

Patients whose blood type is O

Description:

Applying nonsurgical periodontal treatment (scaling and root planning).

Treatment:

Procedure: nonsurgical periodontal treatment