Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome (ARDStrain)

Central Hospital, Nancy, France

Status: Completed

Conditions: ARDS

Study type: Observational

Funder types: Other

Identifiers

NCT02638844

CPRC2013 ARDStrain

Details and patient eligibility

About

Assessment of right ventricular (RV) function in patients with acute respiratory syndrome (ARDS) is warranted because RV failure is frequent and associated with worse outcome. Transthoracic echocardiography is the cornerstone of RV assessment but it remains challenging. Quantification of RV deformation by speckle-tracking imaging echocardiography (STE) is a widely available and reproducible technique that readily provides an integrated analysis of all segments of the RV. This study aims to investigate the accuracy of STE-derived strain parameters in assessing RV function during ARDS.

Enrollment: 49 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with moderate or severe ARDS (Berlin definition)
• receiving mechanical ventilation (>48h estimated length)
• Transthoracic echocardiography performed during the first 36h after ICU admission

Exclusion criteria

• pregnancy
• protected or deprived of Liberty major
• chronic respiratory disease
• history of clinical right heart failure
• chronic heart failure with LVEF < 35%
• severe valvular heart disease
• under 18 or protected-adults