ClinicalTrials.Veeva

Menu

Assessment of Skeletal Maturity Using Proximal Femoral Epiphysis in Patients With Scoliosis

The University of Hong Kong (HKU) logo

The University of Hong Kong (HKU)

Status

Enrolling

Conditions

Idiopathic Scoliosis

Study type

Observational

Funder types

Other

Identifiers

NCT04746417
FVersion 1.0

Details and patient eligibility

About

This study aims to explore the use of proximal femoral head for the assessment of skeletal maturity in patients with idiopathic scoliosis. The aim is to validate the use of the stages of proximal femoral epiphyseal closure in assessing pubertal growth landmarks in this patient cohort. The grading system of this skeletal maturity index will be established and its reliability and reproducibility in clinical use will be examined.

Full description

There are multiple skeletal maturity measures currently in use which were established with reliability in assessing growth. The advantages and shortcomings of each index was previously examined. This study aims to explore the use of proximal femoral epiphysis, which is in close proximity of the radiographic field of the spine, in assessing the growth status of patients with idiopathic scoliosis. The stages of the proximal femoral epiphyseal ossification has been established with specific definitions. The reliability and reproducibility of using these gradings will be examined by orthopaedic surgeons. Subsequently, the assessment of different pubertal growth landmarks using these gradings will be validated, and to see whether these gradings can provide indications of peak growth and growth cessation. Finally, the relationships of such growth assessment using this proximal femoral epiphysis ossification (PFEO) system and the curve progression in idiopathic scoliosis will be studied.

Enrollment

70 estimated patients

Sex

All

Ages

6 to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Idiopathic scoliosis
  • Open triradiate cartilage or open distal radius epiphysis without capping

Exclusion criteria

  • Non-idiopathic scoliosis
  • Patients with growth hormone deficiency or developmental delay
  • Patient has not reached skeletal maturity
  • Defaulted and lost to follow-up

Trial contacts and locations

1

Loading...

Central trial contact

J Cheung

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems