Assessment of Sleep Disturbance as a Biomarker of Disease Activity in a Military Population With Posttraumatic Stress Disorder (SOMMEPT)

Direction Centrale du Service de Santé des Armées

Status

Enrolling

Conditions

Post-traumatic Stress Disorder

Treatments

Behavioral: Sleep recording

Behavioral: Cognitive tasks

Other: Questionnaires

Study type

Observational

Funder types

Other

Identifiers

NCT04581850

2020PRI01

2020-A01808-31 (Other Identifier)

Details and patient eligibility

About

Post-Traumatic Stress Disorder (PTSD) is a public health problem due to both its chronic nature and the low response rate to conventional therapies.

Sleep disorders are the first cause of complaint in patients with PTSD due to night awakenings, difficulty to fall asleep and nightmares.

According to a part of the scientific community, replicative traumatic nightmares represent PTSD's basis mechanism. Traumatic nightmares generate disabling symptoms such as anxiety reactions, while maintaining the symptoms by depriving the individual of good quality sleep. Traumatic nightmares may thus be a sign of PTSD seriousness and chronicity, although their physiological basis remain poorly known.

In the military population, which is highly exposed to psychological traumatism, PTSD prevalence is very high and is associated with severe intensity patterns, a very high frequency of replicative nightmares and a low response to conventional therapies.

Enrollment

190 estimated patients

Sex

All

Ages

18 to 65 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Military or former military
Age between 18 and 65 years old
PTSD group : with a PTSD diagnosis
Control group : without any sleep, psychiatric or neurologic pathology

Exclusion criteria

Diagnosis of progressive psychiatric pathology prior to the traumatic event responsible for PTSD
Sleep pathology prior to the traumatic event responsible for PTSD
Neurological pathology or severe head injury within the last 3 years