Assessment of Suspected Intracranial Malignancy Using 3'-Deoxy-3'18 F-flourothymidine PET

University of Oklahoma (OU)

Status: Terminated

Conditions: Brain Tumor

Treatments: Procedure: FLT-PET scan

Study type: Observational

Funder types: Other

Identifiers

NCT00775320

FLT- Brain Study

Details and patient eligibility

About

The primary objective of this study is to detect and quantify tumor cells of high grade malignant gliomas and metastatic brain lesions both before and after initial surgical resection in a cohort of newly diagnosed patients.

Full description

In this study, 35 patients will be selected to undergoing sequential imaging with FLT-PET. Prior to surgical resection, patients will undergo a preliminary FLT-PET. Additional FLT scans for a maximum of four scans.

Enrollment: 13 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years or older
• Women must not be pregnant or breast feeding
• Histologic or strong radiologic suspicion of high grade malignant glioma or ogliometastatic tumor(s)

Exclusion criteria

• May not have received previous therapy for their malignancy

Trial design

13 participants in 1 patient group

Brain tumor FLT-PET

Description:

Those diagnosed with a brain tumor and are to undergo surgery

Treatment:

Procedure: FLT-PET scan