Assessment of the Effects of Extensive Somatosensory Training on Pain Processing

Aalborg University

Status: Terminated

Conditions: Musculoskeletal Pain

Treatments: Drug: Nerve Growth Factor

Study type: Observational

Funder types: Other

Identifiers

NCT04457466

10042017

Details and patient eligibility

About

Persistent pain may lead to several alterations in the brain activity and sensory perception (i.e. pain). Around 80% of professional musicians experience prolonged episodes of musculoskeletal pain throughout their careers, a percentage that is four times higher than in the general population. With this background, the intended experiment aims at understanding the role of several biological factors associated to sensorimotor training that can lead to alteration of the brain activity and, consequently, pain processing.

Enrollment: 100 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Healthy men and women Speak and understand English.

General exclusion criteria are:

• Pregnancy
• Drug addiction defined as the use of cannabis, opioids or other drugs
• Previous neurologic or mental illnesses
• Presence of a history of trauma or neurologic entrapment syndromes to the arm regions.
• Lack of ability to cooperate
• Frequent computer gamer ( > 9 hours/week)

Trial design

100 participants in 4 patient groups

Healthy musicians

Description:

Men and women aged 18-60, who must be enrolled in a music conservatory performance program or be professionally active, and must speak and understand English.

Treatment:

Drug: Nerve Growth Factor

Healthy non-musicians

Description:

Men and women aged 18-60, must speak and understand English and not have any kind of musical training.

Treatment:

Drug: Nerve Growth Factor

Musicians with chronic pain

Description:

Men and women aged 18-60 with chronic and idiopathic musculoskeletal upper limb and/or neck pain lasting more than 6 months. They must be enrolled in a music conservatory performance program or be professionally active and must speak and understand English.

Treatment:

Drug: Nerve Growth Factor

Non-musicians with chronic pain

Description:

Men and women aged 18-60 with chronic and idiopathic musculoskeletal upper limb and/or neck pain lasting more than 6 months. They must not have any kind of musical training and must speak and understand English.

Treatment:

Drug: Nerve Growth Factor