Assessment of the Effects of Silk Pillowcases on Acne Prone Skin

Integrative Skin Science and Research

Status: Not yet enrolling

Conditions: Acne Vulgaris

Treatments: Other: Silk Pillowcase; Other: Cotton Pillowcase

Study type: Interventional

Funder types: Industry

Identifiers

NCT06142487

i23-11-silk_pillowcase_acne

Details and patient eligibility

About

The purpose of this study is to determine the effects of using silk pillowcases in mild to moderate non-cystic acne prone skin in comparison to cotton pillowcases.

Full description

The investigators will evaluate acne severity/ lesion count, trans-epidermal water loss, and sebum production in participants. There is an equal chance of being assigned a 100% silk pillowcase or 100% cotton pillowcase.

Enrollment: 48 estimated patients

Sex: All

Ages: 15 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Males and females between the ages of 15-45 years of age
• The presence of mild to moderate acne vulgaris based on investigator global assessment
• Presence of at least 5 inflammatory lesions and at least 5 non-inflammatory lesions

Exclusion criteria

• The presence of severe acne as noted by investigator global assessment.
• Those who are unwilling to discontinue systemic antibiotics and benzoyl peroxide for 4 weeks meet the washout criteria prior to enrolling.
• Those who are unwilling to keep their facial regimen consistent throughout the study, and for 1 month prior to enrolling.
• Individuals who are unwilling to wash pillowcase every week using provided detergent.
• Use of isotretinoin within the three months prior to enrolment
• Individuals who primarily sleep on their back
• Current tobacco smoker or a tobacco smoking history of greater than 10 pack year
• Individuals on oral contraceptive pills or progesterone or estrogen containing therapies.
• Individuals who have changed any of their hormonal based contraception within 3 months prior to joining the study
• Individuals with known allergy or sensitivity to Mulberry Silk or Cotton Fibers in fabric

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

48 participants in 2 patient groups

Silk Pillowcase

Experimental group

Description:

100% Mulberry Silk Pillowcase used every night

Treatment:

Other: Silk Pillowcase

Cotton Pillowcase

Active Comparator group

Description:

100% Cotton Pillowcase used every night

Treatment:

Other: Cotton Pillowcase