Assessment of the Efficacy of Rosuvastatin in Patient Groups With a Dissimilar Risk Profile in an Observational Study (HEROS)

AstraZeneca

Status: Completed

Conditions: Cerebrovascular Accident; Diabetes; Peripheral Vascular Disease; Coronary Heart Disease; Hypercholesterolemia

Treatments: Drug: Rosuvastatin

Study type: Observational

Funder types: Industry

Identifiers

NCT00660764

25V07

Details and patient eligibility

About

In an observational multi-centre study (HEROS), the effects of starting treatment with rosuvastatin were assessed, on low-density lipoprotein cholesterol (LDL-C) goal achievement, in patients with a dissimilar high-risk profile who had not been treated with cholesterol lowering drugs at least in the past three months. Also set-up costs of rosuvastatin treatment and proportional changes in LDL-C and high-density lipoprotein cholesterol (HDL-C) were studied.

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who had not been treated with cholesterol lowering drugs at least in the past three months, with an LDL-C 3.2 mmol/l.
• According to the advise of the CBO, and could be included in one of the following risk groups: secondary prevention, DM or primary prevention.
• The general practice investigator made the decision to start treatment with rosuvastatin irrespective of study participation.
• Patient approved to place anonymous results at the disposal of AstraZeneca

Exclusion criteria

• Patients with symptoms of myalgia, myopathy or liver function insufficiency (including raised serum transaminases) which bear a causal relation to the treatment with statins, patients with familiar dyslipidemia and/or patients with contra-indications for treatment with rosuvastatin

Trial design

0 participants in 1 patient group

1

Description:

Patients eligible for the study were patients who had not been treated with cholesterol lowering drugs at least in the past three months, with an LDL-C ≥ 3.2 mmol/l. Patients were aged ≥ 18 years and ≤ 70 years (men) and ≤ 75 years (women), according to the advise of the CBO, and could be included in one of the following risk groups: secondary prevention, DM or primary prevention. The general practice investigator made the decision to start treatment with rosuvastatin irrespective of study participation. Patient approved to place anonymous results at the disposal of AstraZeneca

Treatment:

Drug: Rosuvastatin