Assessment of the Efficacy of Tracheal Oxygen Administration During Bronchoscopy - a Phase II Trial

Catholic University (KU) of Leuven

Status: Unknown

Conditions: Hypoxaemia

Study type: Observational

Funder types: Other

Identifiers

NCT01786642

AETOB

Details and patient eligibility

About

The aim of the present study is to measure the time to correction of O2 saturation when in case of desaturation below 90%, O2 administration is switched from the nasal to the tracheal route at a similar flow rate.

Full description

The development of a flexible bronchoscope with a channel dedicated to O2 administration might allow optimization of the oxygen supplementation during bronchoscopy, which reduces the risk of per- and peri-procedural hypoxemia. The investigators will conduct a pilot study corroborating the hypothesis that tracheal supplementation of oxygen during flexible bronchoscopy is advantageous in comparison to nasal cannula supplementation.

The concept of our trial consists of a mono-centric observational study performed in the endoscopy suite of the Respiratory Division, University Hospitals Leuven. All patients will be given informed consent before inclusion.

The aim of the present study is to measure the time to correction of O2 saturation when in case of desaturation below 90%, O2 administration is switched from the nasal to the tracheal route at a similar flow rate.

Enrollment: 40 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients referred for flexible bronchoscopy

Exclusion criteria

• broncho-alveolar lavage
• endobronchial plugging

Trial design

40 participants in 2 patient groups

conscious

Description:

bronchoscopy without sedative drugs

conscious sedation

Description:

bronchoscopy under midazolam