Assessment of the Health Improvement of Obese Patients After Fecal Microbiota Transplantation (FMT)

Federal Research and Clinical Center of Physical-Chemical Medicine

Status: Completed

Conditions: Obesity; Familial

Treatments: Other: Fecal microbiota

Study type: Interventional

Funder types: Other

Identifiers

NCT04579263

FMT-D1D2

Details and patient eligibility

About

Search for mechanisms of the effect of fecal microbiota transplantation on patients with obesity

Full description

1. To select recipients of fecal samples according to eligibility criteria;
2. To perform fecal microbiota transplantation for patients with obesity;
3. To analyze the efficacy of fecal microbiota transplantation for patients with obesity within six months after therapy.

Enrollment: 2 patients

Sex: Male

Ages: 40 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age of patients - from 18 to 75 years, both sexes;
• patients with obesity (body mass index ≥40
• patient's informed consent to perform fecal microbiota transplantation

Exclusion criteria

• presence of a concomitant chronic infectious disease or malignancy
• patients with a proven allergy to foods not excluded from the donor's diet
• absence of the patient for one or more intermediate stages of the examination.
• informed refusal to continue therapy

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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2 participants in 2 patient groups

Patient with diabetes mellitus type 1 (T1DM)

Experimental group

Description:

Treatment by transplantation of fecal microbiota

Treatment:

Other: Fecal microbiota

Patient with diabetes mellitus type 2 (T2DM)

Experimental group

Description:

Treatment by transplantation of fecal microbiota

Treatment:

Other: Fecal microbiota