Assessment of the Neurovascular Microcirculatory Response in Diabetes Type 1 Patients (NEURODIAB1)

University Hospital, Angers

Status: Completed

Conditions: Diabetes Mellitus Type 1

Treatments: Other: Microvascular assessment

Study type: Interventional

Funder types: Other

Identifiers

NCT02538120

2012-A010008-35

Details and patient eligibility

About

This study aims to see whether or not the diabetes 1 patients have a neurovascular microcirculatory dysfunction using various microvascular tests which have been previously validated.

Microvascular responses will be assessed by Laser Speckle Contrast Imaging and expressed in Laser Speckle Perfusion Units (LSPU).

Full description

The investigators will compare microvascular responses between diabetes type 1 patients with matched control-subjects.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Diabetes type 1 patients
• Matched control-subjects

Exclusion criteria

• Patients or subjects with anti-inflammatory drugs

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Diabetes type 1 patients

Active Comparator group

Description:

The intervention will be : Microvascular assessment with laser speckle contrast imaging

Treatment:

Other: Microvascular assessment

Matched control-subjects

Active Comparator group

Description:

The intervention will be : Microvascular assessment with laser speckle contrast imaging

Treatment:

Other: Microvascular assessment