Assessment of the NIPE in Very Premature Infant Ventilated and Sedated in Neonatal Reanimation. (NIPEpréma)

University Hospital, Lille

Status: Enrolling

Conditions: Reanimation; Pain Measurement; Neonatal

Treatments: Device: Pain measurement during care procedures in neonatal reanimation

Study type: Observational

Funder types: Other

Identifiers

NCT05223790

2021_0238

Details and patient eligibility

About

The Newborn Infant Parasympathetic Evaluation (NIPE) was developed as a method of analysis of the heart rate variability. The monitor gives a value between 0 (low value of the parasympathetic component) and 100 (high value of the parasympathetic component).

So far, the measure of the heart failure variability by using the NIPE in infant born very premature ventilated and sedated in neonatal reanimation has not been realised and validated as an evaluation method of the pain and discomfort related to neonatal care.

Enrollment: 50 estimated patients

Sex: All

Ages: Under 7 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infant born very premature before 34 weeks of amenorrhoea + 0 day
• Age ≤ 7 days
• Admitted in neonatal reanimation
• Sedated, intubated, ventilated

Exclusion criteria

• High frequency oscillation ventilation
• Heart rate non sinusal
• Inotropes and atropine
• Opposition from the guardian of parental authority
• Difficulty of comprehension or communication making the parental information impossible