Assessment of the Relative Increase in Bioavailability of (Non-) Nutrients From a Mixed Salad by Adding Fat Containing Dressing

Unilever

Status: Completed

Conditions: Healthy Subjects

Treatments: Other: Control product: Salad with low dosage fat; Other: Test product: Salad with a high dosage fat

Study type: Interventional

Funder types: Industry

Identifiers

NCT01752764

FDS-DRS-0573

Details and patient eligibility

About

The hypothesis will be tested that fat can also increase absorption of (non)-nutrients from a salad. Therefore we designed the current study to show an increase in relative absorption (bioavailability) of (non-) nutrients from a mixed salad by adding fat containing dressing.

Enrollment: 12 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Main inclusion Criteria:

• Body mass index (BMI) ≥ 18.5 and ≤ 30.0 kg/m2.
• Apparently healthy: no medical conditions, no use of prescribed or over the counter drugs, which might affect study measurements (as judged by study physician)
• Haemoglobin within normal reference range as judged by the study physician.
• Total cholesterol, LDL cholesterol, HDL cholesterol and fasting triglycerides within the normal reference range, as judged by the study physician.

Main exclusion Criteria:

• Reported use of any medically- or self-prescribed diet at the moment of screening, or the intention to use any kind of diet in the period between screening and the end of the study.
• Reported weight loss or gain ≥ 10 % of bodyweight during a period of six months before screening.
• A known food allergy or intolerance.
• A dislike to the foods supplied during the study.
• Use of vitamins or supplements enriched with carotenoid and/or vitamin A and/of vitamin K.
• Known hypothyroidism or hyperthyroidism.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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12 participants in 2 patient groups

Test product

Experimental group

Description:

Test product: Salad with high dosage fat

Treatment:

Other: Control product: Salad with low dosage fat

Other: Test product: Salad with a high dosage fat

Control product

Other group

Description:

Control product: Salad with low dosage fat

Treatment:

Other: Control product: Salad with low dosage fat

Other: Test product: Salad with a high dosage fat