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Assessment of the V600E Mutation in the B-RAF Gene in Chronic Lymphoproliferative Disease (B-RAF V600E)

H

HaEmek Medical Center, Israel

Status

Completed

Conditions

Splenic Marginal Zone Lymphoma
Hairy Cell Leukemia

Study type

Observational

Funder types

Other

Identifiers

NCT01720758
EMC-0124-11-CTIL

Details and patient eligibility

About

The presence of a specific mutation in the gene known as B-RAF has been found in patients who have Hairy Cell Leukemia. In this study this specific mutation known as V600E will be ascertained in peripheral blood samples of patients who have this disease and in a group of patients who have a similar chronic lymphoproliferative conditions such as splenic marginal lymphoma. The finding of this specific mutation will help to verify or exclude the diagnosis of Hairy Cell Leukemia and determine whether patients are in remission.

Enrollment

20 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients over the age of 18 years -

Exclusion criteria

Patients less than 18 years in age or mentally defectives.

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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