Assessment of Two New Electronic Cigarettes in Cigarette Smokers

Virginia Commonwealth University (VCU)

Status: Completed

Conditions: Electronic Cigarettes

Treatments: Other: JUUL electronic cigarette; Other: Own Brand cigarette; Other: IQOS electronic cigarette

Study type: Interventional

Funder types: Other

Identifiers

NCT03435562

HM20012013

Details and patient eligibility

About

The purpose of this study is to determine differences in nicotine delivery, user behavior, subjective effects, and physiological effects, when cigarette smokers use an two new electronic cigarette devices (JUUL and IQOS) relative to their using their own brand of cigarettes.

Enrollment: 22 patients

Sex: All

Ages: 21 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria--participants must be:

• healthy (determined by self-report)
• between the ages of 18-55
• willing to provide informed consent
• able to attend the lab and abstain from tobacco/nicotine as required and must agree to use designated products according to study protocol
• cigarette smokers

Exclusion Criteria:

• Women if they are breast-feeding or test positive for pregnancy (by urinalysis) at screening.
• Individuals who weigh less than 110 pounds

Some study details about the eligibility criteria are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.

Trial design

22 participants in 1 patient group

electronic cigarette vs own brand use

Experimental group

Description:

Participants will come in for three session. During one session, participants will first complete a 10-puff product use bout with JUUL, and then a 90-minute ad lib product use bout with JUUL (the session will be approximately 3 hours). During one session, participants will first complete a 10-puff product use bout with IQOS, and then a 90-minute ad lib product use bout with IQOS (the session will be approximately 3 hours). During one session, participants will first complete a 10-puff product use bout with their own brand cigarettes, and then a 90-minute ad lib product use bout with their own brand cigarette (the session will be approximately 3 hours). The order of the sessions will be determined randomly and data about session will not be recorded or used in the analysis.

Treatment:

Other: Own Brand cigarette

Other: JUUL electronic cigarette

Other: IQOS electronic cigarette