Association Between Ambient Temperature and Myocardial Injury After Noncardiac Surgery in Adults

Hao Li

Status: Completed

Conditions: MINS

Treatments: Other: MINS

Study type: Observational

Funder types: Other

Identifiers

NCT07079891

20256030

Details and patient eligibility

About

This single-center retrospective cohort study enrolled patients aged ≥18 years who underwent noncardiac surgery between January 2014 and December 2023. The exposure variable was the 7-day average preoperative ambient temperature in Beijing. Univariate and multivariate logistic regression models were used to evaluate the association between temperature and MINS. Inverse probability of treatment weighting (IPTW) analysis was performed to enhance the robustness of the findings. Subgroup analyses were performed across predefined clinical strata.

Enrollment: 143,095 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ≥18 years
• underwent noncardiac surgery under general anesthesia

Exclusion criteria

• American Society of Anesthesiologists (ASA) classification V;
• outpatient, hysteroscopic, or body surface surgeries
• surgery duration ≤30 min
• absence of postoperative high-sensitivity troponin T (hs-TnT) testing within 30 days
• incomplete clinical data (≥20% missing data)

Trial design

143,095 participants in 4 patient groups

moderate heat (22.8℃-29.2℃)

Treatment:

Other: MINS

extreme heat (≥29.2℃)

Treatment:

Other: MINS

extreme cold (≤-3.5℃)

Treatment:

Other: MINS

moderate cold (-3.5℃-22.8℃)

Treatment:

Other: MINS