Association Between Apical Periodontitis and Psoriasis Vulgaris

University of Siena

Status: Completed

Conditions: Apical Periodontitis

Study type: Observational

Funder types: Other

Identifiers

NCT06436339

PSY003

Details and patient eligibility

About

The aim of the present cross-sectional study is to assess the presence of AP and caries in psoriasis vulgaris individuals and to examine whether these medications influence these oral conditions. Therefore, 154 patients diagnosed with psoriasis were included in the study and subjected to oral examination to assess for presence of periapical lesions and caries experience.

Full description

The aim of the study is to evaluate the prevalence of apical periodontitis (AP) and caries in subjects with psoriasis vulgaris. 152 patients with psoriasis vulgaris were included in the study. The severity and extent of psoriasis were assessed according to The Psoriasis Area Severity Index (PASI), the Body Surface Area (BSA), and the Physician's Global Assessment Scale (PGA). Periapical status was assessed through dental examination and periapical radiographs. Data regarding Periapical Index (PAI), caries experience expressed as the Decayed, Missing, Filled Teeth Index (DMFT), and psoriasis medications were recorded. A predictive logistic regression model for the presence of AP and a linear regression model were then built to relate the severity and extent of AP to the type of drug therapy taken for psoriasis and to the severity and extent of the skin disease.

Enrollment: 152 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 18 and 70
• Ability and willingness to give written consent;
• Presence of at least 6 teeth.
• Diagnosis of Psoriasis Vulgaris
• Other systemic diseases apart from psoriasis

Exclusion criteria

• diagnosis of periodontitis
• inability or unwillingness to give informed consent;
• periodontal treatment within the previous 6 months;
• ongoing immunosuppressive treatments or antibiotic therapy for other systemic diseases;
• pregnant or on lactation;
• additional comorbidities
• non endodontic lesions in maxilla/mandible;
• AP diagnosed on teeth with inadequate endodontic treatments and coronal restorations