Association Between Clinical Subtypes and Prognosis in Radiation Rectal Injury

Sun Yat-sen University

Status: Enrolling

Conditions: Radiation Proctitis; Radiotherapy

Study type: Observational

Funder types: Other

Identifiers

NCT07378631

CRP202501

Details and patient eligibility

About

This is a prospective, observational study aimed at exploring the associations between the clinical subtypes of radiation rectal injury and prognosis. The study is planed to commence in November 2025 and prospectively observe 150 patients. During the study period, researchers will not intervene in clinical treatment decisions but will only collect patient clinical information, intestinal endoscopy/imaging/pathological data, test results, and follow-up data. The study results will fill the evidence gap in this field, advance the diagnosis and treatment of radiation-induced rectal injury, and provide scientific support for improving the prognosis of similar patients.

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. 18-80 years;
2. Diagnosed with radiation rectal injury.

Exclusion criteria

1. Ongoing cancer therapy;
2. Tumor recurrence or metastasis.

Trial design

150 participants in 1 patient group

Chronic radiation proctitis

Description:

Patients diagnosed with chronic radiation proctitis