Association Between Handgrip Strength and Small Airway Disease in Patients With Stable Chronic Obstructive Pulmonary Disease

Thammasat University

Status: Enrolling

Conditions: COPD

Treatments: Diagnostic Test: Handgrip strength

Study type: Observational

Funder types: Other

Identifiers

NCT06223139

MTU-EC-IM-0-215/65

Details and patient eligibility

About

The goal of this observational study is to investigate the correlation between handgrip strength and small airway disease among patients with chronic obstructive pulmonary disease (COPD). The main question it aims to answer is:

• Is handgrip strength correlated with small airway disease in COPD patients? Participants will perform handgrip strength test and impulse oscillometry (IOS).

Full description

This is a cross-sectional study in COPD patients. COPD patients aged 40 years or older were included. Handgrip strength test and impulse oscillometry will be tested in each patient. Handgrip strength will be measured using a hand dynamometer. Small airway disease will be assessed using IOS.

Enrollment: 62 estimated patients

Sex: All

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COPD patients aged 40 years or older
• Confirmed diagnosis by spirometry (post-bronchodilator FEV1/FVC <0.7)
• Smoking history 10 pack-years or more

Exclusion criteria

• COPD exacerbation within 3 months
• Inability to perform handgrip strength test or impulse oscillometry

Trial design

62 participants in 1 patient group

COPD

Description:

COPD patients aged 40 years or older with a post-bronchodilator ratio of forced expiratory volume in one second (FEV1) to forced vital capacity (FVC) <0.7.

Treatment:

Diagnostic Test: Handgrip strength