Association Between Human Immunodeficiency Virus (HIV) Infection and Male Hypogonadism

National Taiwan University

Status: Enrolling

Conditions: Hypogonadism; Ovarian

Treatments: Diagnostic Test: Testosterone

Study type: Observational

Funder types: Other

Identifiers

NCT04760574

202010105RIND

Details and patient eligibility

About

Cross-sectional study investigating the prevalence of hypogonadism in HIV-infected MSM population

Full description

In this study, we conduct a cross-sectional study investigating the prevalence of hypogonadism in HIV-infected MSM population. Age-matched non-HIV infected MSM group will be used as comparison group. We will also determine the risk factors associated with male hypogonadism (age, duration of HIV infection, comorbidities, BMI, ART use). Correlation will be made between serum testosterone levels and sexual function, vitality, exercise capacity, mood, and bone mineral density.

Enrollment: 1,200 estimated patients

Sex: Male

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• HIV-infected men who have sex with men
• HIV non-infected men

Exclusion criteria

• Use of testosterone supplement, anabolic steroid in the past one year.
• History of pituitary , adrenal or gonad diseases
• History of pituitary surgery or radiation therapy
• History of systemic chemotherapy
• Active opportunistic infection under treatment
• Cancer
• Severe hepatic, renal or cardiac impairment

Trial design

1,200 participants in 2 patient groups

Case group

Description:

HIV infected men who have sex with men

Treatment:

Diagnostic Test: Testosterone

Control group

Description:

HIV non-infected men

Treatment:

Diagnostic Test: Testosterone