Association Between Iron Reserves and Perioperative Neurocognitive Disorders

Chinese PLA General Hospital (301 Hospital)

Status: Completed

Conditions: Perioperative Neurocognitive Disorders

Treatments: Other: no intervention

Study type: Observational

Funder types: Other

Identifiers

NCT06502912

PLAGH-AOC-R02

Details and patient eligibility

About

Iron metabolism disorder have been identified as the pivotal contributor in the pathogenesis and progression of perioperative neurocognitive disorders. However, the association between iron reserves and perioperative neurocognitive disorders risk remains elusive. This retrospective cohort study aimed to explore the impact of preoperative serum ferritin levels on the risk of postoperative delirium in elderly patients undergoing non-neurosurgical and non-cardiac procedures.

Enrollment: 12,984 patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Geriatric surgical patients ≥65 years old

Exclusion criteria

• preoperative use of antipsychotics
• diagnosis or history description of preoperative cognitive disorders including dementia and Parkinson's

Trial design

12,984 participants in 1 patient group

elderly patients (aged ≥ 65 years)

Description:

elderly patients undergoing non-neurosurgical and non-cardiac procedures

Treatment:

Other: no intervention