Association Between Multiple Coagulation-related Factors and Lymph Node Metastasis in Patients With Gastric Cancer: A Retrospective Cohort Study (MA)

Shandong First Medical University

Status: Enrolling

Conditions: Lymph Node Metastasis; Gastric Cancer Stage

Treatments: Diagnostic Test: coagulation-related factors

Study type: Observational

Funder types: Other

Identifiers

NCT05592925

FTian

Details and patient eligibility

About

We initially selected a total of 1128 patients with primary gastric cancer who presented at Shandong Provincial Hospital between January 2018 and October 2022, and retrospectively collected their clinical and pathological data. And retrospectively analyzed preoperative baseline characteristics, preoperative laboratory tests, and postoperative pathological results for these patients

Enrollment: 516 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

1. patients with primary gastric malignant tumors,
2. patients who underwent radical resection of gastric cancer,
3. patients with a postoperative pathology of adenocarcinoma or signet ring cell carcinoma according to the WTO pathological classification,

Exclusion criteria

1. patients who have distant metastases, such as liver or lung metastases, were found on preoperative ultrasound and computed tomography (CT) examinations,
2. patients who have received preoperative neoadjuvant chemotherapy,
3. patients who take anticoagulant drugs (such as aspirin) prior to surgery,
4. patients who had any previous coagulation disorder.

Trial design

516 participants in 2 patient groups

N0

Description:

gastric cancer patients with no lymph node metastasis

Treatment:

Diagnostic Test: coagulation-related factors

N+

Description:

gastric cancer patients with lymph node metastasis, including patients with N1, N2 and N3 stage cancer

Treatment:

Diagnostic Test: coagulation-related factors