Association Between Peri-procedural Myocardial Injury and Quantitative Blood Flow Ratio

Xiamen University

Status: Completed

Conditions: Coronary Arterial Disease (CAD)

Study type: Observational

Funder types: Other

Identifiers

NCT07110298

QFR AND PMI

Details and patient eligibility

About

to apply angiography-based quantitative blood flow ratio to quantify the severity of the stenosed coronary artery prior to percutaneous coronary intervention, and monitor per-procedural myocardial injury based on the troponin level.Finally, to find the relationship between quantitative blood flow ratio results and myocardial injury degree.

Enrollment: 200 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• unstable angina patients

Exclusion criteria

• (1) multivessel diseases needed to be bypassed; (2) no track of high-sensitivity troponin I (hs-CTNI) level after PCI; (3) the elevated hs-CTNI level before PCI; (4) patients refusal to PCI; (5) side branch occlusion after PCI; (6) PCI failure with the main vessels occlusion; (7) eGRF (estimated glomerular filtration rate) less than 30ml/min/1.73m2; (8) no acquisition of QFR results because of the non-ideal angiographic quality.

Trial design

200 participants in 1 patient group

post- procedural serum hs-cTNI level more than three times of URL

Description:

cohort divided into two groups based on the post- procedural serum hs-cTNI level