Association Between Preoperative Hyperglycemia and Postoperative Delirium in Geriatric Hip Fracture Patients

Wenbo Ding

Status: Completed

Conditions: Hip Fractures; Hyperglycemia; Postoperative Delirium

Study type: Observational

Funder types: Other

Identifiers

NCT06473324

DDZX-20231121

Details and patient eligibility

About

This retrospective study aims to collect electronic medical record data from Dandong central hospital spanning from January 2013 to November 2023. The collected data does not contain any personally identifiable information or breach privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The research aims to investigate the correlation between preoperative blood glucose levels in elderly hip fracture patients and postoperative delirium.

Full description

A retrospective observational study is planned to explore specific phenomena or associations using electronic medical record data. The collected data does not contain any personally identifiable information or compromise privacy. Additionally, this study design does not involve active intervention measures or patient recruitment. The study data is sourced from the electronic medical record system of hospitalized patients and has received approval from the hospital's research center, with ongoing supervision by the hospital's ethics committee. The study aims to investigate the correlation between preoperative blood glucose levels in hip fracture patients and postoperative complications.

The retrospective study aims to collect electronic medical record data spanning from January 2013 to November 2023. The data collection process is consistently monitored and verified by the hospital's ethics committee. Throughout the study, adherence to the ethical principles outlined in the 1964 Helsinki Declaration is ensured, and institutional review board (IRB) approval has been obtained for all aspects of the research.

The study aims to provide valuable evidence-based medicine for clinical practitioners by examining the relationship between preoperative persistent hyperglycemia in elderly hip fracture patients and postoperative delirium. Furthermore, it seeks to offer clinical insights for early identification and intervention management of high-risk postoperative delirium patients (POD).

Enrollment: 2,031 patients

Sex: All

Ages: 60 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients who have undergone surgical treatment for hip fractures.

Exclusion criteria

1. Multiple or pathological hip fractures.
2. Emergent surgery.
3. Age below 60 years.
4. Incomplete electronic medical records or preoperative blood glucose levels were assessed fewer than two times.
5. Presence of neurological and psychiatric disorders, except dementia.

Trial design

2,031 participants in 2 patient groups

hyperglycaemia group

Description:

Blood glucose level ≥ 6.1 mmol/L

hypoglycaemic group

Description:

Blood glucose level \< 6.1 mmol/L