Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery (DECONGEST)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Cardiorenal Syndrome

Treatments: Procedure: diuretic use

Study type: Observational

Funder types: Other

Identifiers

NCT03684876

PI 2018_843_012

Details and patient eligibility

About

Following cardiac surgery, right ventricular function may be altered leading to increase central venous pressure and decrease in renal blood flow. The investigator's standard care includes use of diuretic to avoid interstitial fluid accumulation. The aim of the study is to assess cardiac and renal function before and after depletion by using diuretics

Full description

The study will compare cardiac and renal data before and 6 hours after use of diuretic

• Echocardiographic measure of right function (S wave, TAPSE, ventricle surfaces, inferior vena cava diameter) and left function (LVEF, cardiac output
• Renal function: cumulative diuresis, creatinine level variation and incidence of acute kidney injury using KDIGO classification (creatinine level>26.5 or diuresis<0.05 ml kg-1 h-1)

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

patient undergoing elective cardiac surgery under cardiopulmonary bypass

Exclusion criteria

• heart transplantation
• use of vasopressor
• chronic renal disease (DGF under 30 ml min-1)
• endocarditis
• patient under ECLS or CPIA
• patient under 18-year-old